Manchester City are 1.62 to complete a hat-trick of title triumphs in bwin’s Premier League outright winner odds following the announcement of next season’s fixtures.
The back-to-back champions will kick off their campaign with a tricky trip to West Ham on Sunday, August 7.
Pep Guardiola has already bolstered his star-studded squad with the capture of Norway striker Erling Haaland from Borussia Dortmund for a bargain £51.2million.
Argentina forward Julian Alvarez has also arrived from River Plate for a fee in the region of £14m, as City chase a fifth title in six seasons.
They play two of the promoted sides at home in August and do not face any of the traditional ‘big six’ until mid-September, when they host Tottenham.
Main rivals Liverpool, who finished just a point behind last term, can be backed at 3.25 and will visit Fulham first up.
The Reds, who claimed a 19th title in 2020, have swooped to sign Uruguay front man Darwin Nunez from Benfica for an initial fee of £64m.
Teenage winger Fabio Carvalho has switched to Liverpool from the Cottagers, so could be in line for an early return to his former club.
Chelsea were best of the rest last season but are 17.0 this time following a turbulent spell off the pitch, with long-time benefactor Roman Abramovich forced to sell the club.
Thomas Tuchel will hope the focus is fully back on playing matters by the time the Blues travel to Everton on the opening weekend.
Gunners kick off new season at Selhurst
Arsenal will feature in the curtain-raiser on August 5 when facing Crystal Palace at Selhurst Park.
The pressure is on Mikel Arteta after missing out on Champions League football and the Gunners are 51.0 in bwin’s Premier League outright winner odds.
Tottenham pipped their north London rivals to fourth spot last season and are rated 15.0 third favourites to finish top for the first time since 1961.
Antonio Conte has already strengthened his squad with the capture of Croatia veteran Ivan Perisic from Inter Milan.
Erik ten Hag has been brought in to turn around Manchester United’s flagging fortunes and will begin his reign by hosting Brighton.
The Red Devils, quoted at 29.0 for a 21st title, slumped to sixth last term, 35 points adrift of neighbours City, and must embark on a rebuilding process.
Paul Pogba, Juan Mata, Jesse Lingard, Nemanja Matic and Edinson Cavani have all moved on and some strong reinforcements are required.
August 5 – Crystal Palace vs Arsenal
August 6 – Bournemouth vs Aston Villa, Everton vs Chelsea, Fulham vs Liverpool, Leeds vs Wolves, Leicester vs Brentford, Newcastle vs Nottingham Forest, Tottenham vs Southampton
August 7 – Manchester United vs Brighton, West Ham vs Manchester City
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