West Ham spent the international break flying high in third in the Premier League and victory at Wolves would be further proof they are genuine top-four challengers. Wolves are also in fine form, with both teams picking up 16 points from their last eight matches, so this is a tough test for the Hammers.
There have already been five managerial changes in the Premier League this season but Ole Gunnar Solskjaer survived the international break and now takes his Manchester United team to struggling Watford. United have only won one of their last six games but are still firm favourites to get the better of Watford.
Chelsea dropped points at home prior to the international break and the Premier League leaders have had a frustrating wait to make amends. Burnley became the first team other than title contenders Liverpool and Manchester City to take points off Chelsea this season with a 1-1 draw at Stamford Bridge.
Newcastle cannot just wait until January signings arrive to step up their relegation fight and new manager Eddie Howe will be desperate to make a winning start at St James’ Park. His first three home matches in charge are against fellow strugglers Brentford, Norwich and Burnley so Howe has an early chance to get the Toon Army onside.