La Roja have to overcome the shock departure of head coach Julen Lopetegui but an impressive qualifying campaign is still reflected in the Spain World Cup 2018 odds.
Lopetegui succeeded Vicente del Bosque following poor performances in Brazil four years ago and at Euro 2016.
Spain suffered an early exit at the last World Cup after starting out with a 5-1 loss to Holland and a 2-0 defeat by Chile.
Two years ago, La Roja made it safely through their group but were then beaten 2-0 by Italy in the first knockout round.
However, the composure and consistency which had previously helped them to pick up three straight major trophies was back in evidence on the road to Russia 2018.
They dropped just two points from 10 games, when drawing 1-1 with Italy in Turin, and racked up 36 goals, whilst conceding only three times.
March’s friendlies provided more encouragement, with a 1-1 Dusseldorf draw versus Germany followed by a 6-1 thrashing of Argentina in Madrid.
Portugal will provide stiff opposition first up in Sochi, but it will be a major surprise if Spain don’t then ease past Iran and Morocco.
Odds correct on date of publication: 21/05/2018
Inspirational captain Sergio Ramos played a leading role in the 2010 World Cup triumph and two European Championship wins in 2008 and 2012.
Despite passing 150 international appearances, the Real Madrid defender is still only 32 and showing no signs of decline.
Barcelona centre-half Gerard Pique provides further experience at the heart of a rock-solid defence, with Manchester United goalkeeper David de Gea ready to deal with anything that does get through.
Andres Iniesta and David Silva are stalwarts in midfield, while Real Madrid duo Isco and Marco Asensio have both made good progress in recent seasons.
Isco was particularly impressive when bagging a brace in last October’s 3-0 demolition of Italy at the Bernabeu.
Up front, Atletico Madrid target man Diego Costa completes a strong spine in this well-balanced unit.
Rank (world): 6
WC appearances: 14
Best effort: Won in 2010
Road to Russia
Israel 0-1 ESP
ESP 3-0 Albania
Liechtenstein 0-8 ESP
ESP 3-0 Italy
Macedonia 1-2 ESP
ESP 4-1 Israel
ESP 4-0 Macedonia
Albania 0-2 ESP
David de Gea (GK)
Sergio Ramos (D)
Gerard Pique (D)
Andres Iniesta (M)
David Silva (M)
Diego Costa (F)