The holders are in a tough section but that hasn't stopped plenty of punters from supporting this talented team to force down the Portugal Euro 2020 odds.
Five years ago, it was a series of strong defensive displays during the knockout rounds which helped the Navigators to lift the trophy, with only one goal conceded in four matches.
Russia 2018 was a bit of a let-down, but more success in the inaugural Nations League competition reinforced the view that Fernando Santos has an outstanding squad to work with.
Much of their forward play obviously revolves around the great Cristiano Ronaldo, who has scored more than a hundred international goals during his incredible career.
However, several members of the supporting cast are now stars in their own right after going from strength to strength in recent years.
Manchester United goal machine Bruno Fernandes, Manchester City playmaker Bernardo Silva, Liverpool recruit Diogo Jota and Atletico Madrid's big-money buy Joao Felix add to the attacking options.
Goalkeepers: Anthony Lopes (Lyon), Rui Patricio (Wolves), Rui Silva (Granada)
Defenders: Joao Cancelo (Manchester City), Ruben Dias (Manchester City), Jose Fonte (Lille), Raphael Guerreiro (Dortmund), Nuno Mendes (Sporting), Pepe (Porto), Nelson Semedo (Wolves)
Midfielders: William Carvalho (Real Betis), Danilo (PSG), Bruno Fernandes (Manchester United), Goncalo Guedes (Valencia), Joao Moutinho (Wolves), Ruben Neves (Wolves), Sergio Oliveira (Porto), Joao Palhinha (Sporting), Pote (Sporting), Renato Sanches (Lille), Bernardo Silva (Manchester City)
Forwards: Joao Felix (Atletico Madrid), Diogo Jota (Liverpool), Cristiano Ronaldo (Juventus), Andre Silva (Eintracht Frankfurt), Rafa Silva (Benfica)