Given their record against Manchester City last season, the last thing Tottenham Hotspur needed was for the international break to strip them of several key men before their trip to the Etihad.
Hugo Lloris and Nacer Chadli are both injury doubts, while Emmanuel Adebayor and Erik Lamela could be rested after gruelling long trips to play for their country.
However, if Mauricio Pochettino can get everyone fit and firing, he should turn to the towering Belgian to lead the line agains the Premier League champions.
Spurs are a lengthy 6/1 to beat City, unsurprising really given that the Sky Blues stuck 11 past them in two wins last season.
The hosts are 1/2 favourites to win the match, with the draw priced at 10/3.
Perhaps Pochettino’s main worry so far this season has been the lack of form shown by Adebayor, who has scored just once in all competitions.
The Argentine manager is hardly well-stocked with other attacking options, with Roberto Soldado still looking far from a £26m striker and Harry Kane likely viewed as too green to start upfront against City.
Step forward Chadli, currently the club’s leading scorer having notched four times in the Premier League already, and available at 19/4 to notch anytime in Manchester having also bagged for Belgium during the break.
The 25-year-old scored Spurs’ goal away at Arsenal in their 1-1 draw in a match where he often payed alongside Adebayor as Pochettino rejigged his system.
Chadli’s ability to hang on the last defender was shown at the Emirates when he latched onto Lamela’s throughball after Spurs had won possession high up the pitch.
Pochettino will rely on similar quick attacks at the Etihad, and Chadli also has the physical presence to hold up the ball and give his defence some respite.
In addition, moving Chadli forward would allow Pochettino to bring in Aaron Lennon, whose main contribution to Spurs over the past couple of seasons has been some fine defensive tracking back, an asset that would be very useful against City.