Liverpool are 8/5 favourites to win Europa League after the draw for the semi-finals.
Prior to the tombola the Anfield side had been outright market leaders at 7/4.
Sevilla were also trimmed from 23/10 to 2/1 after landing Shakhtar Donestk, 6/1 outsiders to win the trophy, at the last-four stage.
The odds compilers reacted positively in their assessment of the significance of Liverpool drawing Villarreal, pushing out El Submarino Amarillo half a point to 15/4.
Resisting the temptation to leave the Reds’ odds unchanged represents a significant show of faith given their foes’ renowned strength at the Madrigal.
Marcelino Garcia Toral’s men have won all bar six of their home games this term, beating both Atletico and Real Madrid along the way and holding Barcelona 2-2.
Inseparable in the first-leg match betting at 8/5 the pair, Anfield’s finest are 3/5 to reach the semi-final at Villarreal’s expense, with their adversaries 27/20 to progress.
Confidence in Sevilla’s ability to dispose of Shakhtar is even greater, with the Rojiblancos 6/4 favourites to win their first leg in Ukraine.
Unai Emery’s reigning champions are 53/100 to reach their third Europa League final in succession, while the Miners are 7/5.
The tie is a re-run of their round-of-16 meeting in the UEFA Cup of 2006/07, an auspicious omen for the Spaniards who prevailed by the odd goal in nine and went on to win the competition that year.